Retinoblastoma 1 anticorps (AA 550-600)

N° du produit ABIN7449625

Cet anticorps Lapin Polyclonal détecte spécifiquement Retinoblastoma 1 dans IP. Il présente une réactivité envers Humain.

Aperçu rapide pour Retinoblastoma 1 anticorps (AA 550-600) (ABIN7449625)

Antigène: Retinoblastoma 1 (RB1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoblastoma 1 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-Retinoblastoma 1 anticorps

Épitope: AA 550-600

Fonction: Rabbit anti-Rb1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 550 and 600

Isotype: IgG

Information d'application

Indications d'application:

IP: 10 - 15 μg/mg lysate

WB: Not recommended.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Retinoblastoma 1

Antigène: Retinoblastoma 1 (RB1)

Autre désignation: Rb1

Sujet: Background: Retinoblastoma 1 (Rb1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. Rb1 has also been found to stabilize constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma [taken from NCBI Entrez Gene (GeneID: 5925)].

ID gène: 5925

NCBI Accession: NP_000312

UniProt: P06400

Pathways: Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy