Recombinant IDO1 anticorps (AA 1-403)

N° du produit ABIN7449662

L’anticorps Lapin Monoclonal anti-IDO1 a été validé pour WB et IP. Il convient pour détecter IDO1 dans des échantillons de Humain.

Aperçu rapide pour Recombinant IDO1 anticorps (AA 1-403) (ABIN7449662)

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IDO1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: BLR040F

Détail du produit anti-IDO1 anticorps

Épitope: AA 1-403

Fonction: Rabbit anti-IDO1 Recombinant Monoclonal Antibody [BLR040F]

Immunogène: residues 1-403 (full length)

Isotype: IgG

Information d'application

Indications d'application:

IP: 15 µL/1 mg lysate

WB: 17:40:00

Restrictions: For Research Use only

Stockage

Concentration: 400 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur IDO1

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Autre désignation: IDO1

Sujet: Background: Indoleamine 2,3-dioxygenase (IDO1) is a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. IDO1 acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. It is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan [taken from NCBI Entrez Gene (Gene ID: 3620)].

ID gène: 3620

NCBI Accession: NP_002155

UniProt: P14902

Pathways: Activated T Cell Proliferation