ube3a anticorps (AA 400-450)

N° du produit ABIN7449675

Cet anticorps anti-ube3a est un anticorps Lapin Polyclonal détectant ube3a dans WB et IP. Adapté pour Humain et Souris.

Aperçu rapide pour ube3a anticorps (AA 400-450) (ABIN7449675)

Antigène: ube3a (Ubiquitin Protein Ligase E3A (ube3a))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ube3a est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-ube3a anticorps

Épitope: AA 400-450

Fonction: Rabbit anti-E6AP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 400 and 450

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ube3a

Antigène: ube3a (Ubiquitin Protein Ligase E3A (ube3a))

Autre désignation: E6AP

Sujet: Background: E6AP is an E3 ubiquitin ligase. Inheritance of a mutant maternal copy of this gene results in Angelman syndrome (AS) which is characterized by severe mental retardation, seizures, ataxia, and EEG abnormalities. E6AP interacts with the type 16 and 18 human papillomavirus E6 oncoprotein which results in the targeting of p53 for degradation via the ubiquitin-proteasome system.

ID gène: 7337

NCBI Accession: NP_000453

UniProt: Q05086

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway