Neurofibromin 1 anticorps (C-Term)

N° du produit ABIN7449677

L’anticorps Lapin Polyclonal anti-Neurofibromin 1 a été validé pour WB et IP. Il convient pour détecter Neurofibromin 1 dans des échantillons de Humain et Souris.

Aperçu rapide pour Neurofibromin 1 anticorps (C-Term) (ABIN7449677)

Antigène: Neurofibromin 1 (NF1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurofibromin 1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Neurofibromin 1 anticorps

Épitope: C-Term

Fonction: Rabbit anti-NF1 Antibody, Affinity Purified

Homologie: Rat

Purification: Affinity Purified

Immunogène: between AA 2760 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Neurofibromin 1

Antigène: Neurofibromin 1 (NF1)

Autre désignation: NF1

Sujet: Background: Inactivating mutations in NF1 (neurofibromin 1) result in neurofibromatosis type I (NF1) which is characterized by Schwann cell neurofibromas, café-au-lait spots, and benign lesions of the iris. At the cellular level, NF1 functions as a negative regulator of Ras activity. Loss of NF1 leads to increased levels of active Ras-GTP which is important for the formation and maintenance of Schwann cell tumors.

ID gène: 4763

NCBI Accession: NP_000258

UniProt: P21359

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity