MED24 anticorps (AA 939-989)

N° du produit ABIN7449847

Cet anticorps Lapin Polyclonal détecte spécifiquement MED24 dans WB et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour MED24 anticorps (AA 939-989) (ABIN7449847)

Antigène: MED24 (Mediator Complex Subunit 24 (MED24))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED24 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-MED24 anticorps

Épitope: AA 939-989

Fonction: Rabbit anti-TRAP100/MED24 Antibody, Affinity Purified

Homologie: Rat,Chicken

Purification: Affinity Purified

Immunogène: between AA 939 and 989

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MED24

Antigène: MED24 (Mediator Complex Subunit 24 (MED24))

Autre désignation: TRAP100/MED24

Sujet: Background: TRAP100/MED24 is a component of the multisubunit mediator complex that functions as an interface between gene-specific transcription factors and the RNA Pol II/general transcription factor machinery. The mediator complex was first identified as a coactivator of the thyroid hormone receptor and has since been observed to function as a coactivator of a variety of transcription factors. TRAP100/MED24 associates with mediator subunit TRAP220. Both are essential to mouse development and play a role in androgen receptor-mediated transcription. Studies in zebrafish have shown that TRAP100/MED24 is also important to retinal development.

ID gène: 9862

NCBI Accession: NP_055630

UniProt: O75448

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity