MAML1 anticorps (AA 75-125)

N° du produit ABIN7449893

L’anticorps Lapin Polyclonal anti-MAML1 a été validé pour WB et IP. Il convient pour détecter MAML1 dans des échantillons de Humain.

Aperçu rapide pour MAML1 anticorps (AA 75-125) (ABIN7449893)

Antigène: MAML1 (Mastermind-Like 1 (MAML1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAML1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-MAML1 anticorps

Épitope: AA 75-125

Fonction: Rabbit anti-MAML1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 75 and 125

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MAML1

Antigène: MAML1 (Mastermind-Like 1 (MAML1))

Autre désignation: MAML1

Sujet: Background: There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML1 is a critical coactivator for NOTCH signaling. MAML1 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML1 has been observed to interact with p300 to acetylate histones H3 and H4. MAML1 also interacts with p53 and functions independent of NOTCH signaling, as a coactivator of p53 target genes.

ID gène: 9794

NCBI Accession: NP_055572

UniProt: Q92585

Pathways: Signalisation Notch, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development