SHANK3 anticorps (AA 1475-1525)

N° du produit ABIN7449919

Cet anticorps Lapin Polyclonal détecte spécifiquement SHANK3 dans WB et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour SHANK3 anticorps (AA 1475-1525) (ABIN7449919)

Antigène: SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHANK3 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-SHANK3 anticorps

Épitope: AA 1475-1525

Fonction: Rabbit anti-SHANK3 Antibody, Affinity Purified

Homologie: Rat

Purification: Affinity Purified

Immunogène: Between AA 1475 and 1525

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SHANK3

Antigène: SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))

Autre désignation: SHANK3

Sujet: Background: SH3 and multiple ankyrin repeat domains 3 (SHANK3) seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. SHANK3 may play a role in the structural and functional organization of the dendritic spine and synaptic junction. [taken from the Universal Protein Resource (UniProt) Q9BYB0].

ID gène: 85358

NCBI Accession: NP_277052

UniProt: Q9BYB0

Pathways: Synaptic Membrane, Tube Formation, Regulation of long-term Neuronal Synaptic Plasticity