Adenylosuccinate Lyase anticorps (AA 200-250)
Aperçu rapide pour Adenylosuccinate Lyase anticorps (AA 200-250) (ABIN7449945)
Antigène
Voir toutes Adenylosuccinate Lyase (ADSL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 200-250
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Fonction
- Rabbit anti-Adenylosuccinate Lyase/ADSL Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- Between AA 200 and 250
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Isotype
- IgG
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Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- Adenylosuccinate Lyase (ADSL)
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Autre désignation
- Adenylosuccinate Lyase/ADSL
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Sujet
- Background: Adenylosuccinate Lyase / ADSL is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and, in some cases, growth retardation associated with muscle wasting and epilepsy [taken from NCBI Entrez Gene (Gene ID: 158)].
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ID gène
- 158
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UniProt
- P30566
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Pathways
- Ribonucleoside Biosynthetic Process
Antigène
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