Estrogen Receptor alpha anticorps (C-Term)

N° du produit ABIN7450221

Cet anticorps anti-Estrogen Receptor alpha Polyclonal Lapin (ABIN7450221) détecte spécifiquement Estrogen Receptor alpha dans WB et IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Estrogen Receptor alpha anticorps (C-Term) (ABIN7450221)

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Estrogen Receptor alpha est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Estrogen Receptor alpha anticorps

Épitope: C-Term

Fonction: Rabbit anti-Estrogen Receptor Alpha Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 550 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Estrogen Receptor alpha

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Autre désignation: Estrogen Receptor Alpha

Sujet: Background: The estrogen receptor (ER) is the steroid-hormone nuclear receptor that binds estrogen and functions to activate genes involved in a variety of biological processes. Two forms of the ER, ER alpha and ER beta, are encoded by independent genes, and each plays different roles in gene regulation. Additional variants of ER beta have also been reported, these include ERb2, ERb3, ERb4, and ERb5. All forms of the ER have the ability to heterodimerize with each other. Differences in localization and concentrations as well as heterodimerization among the variants may serve to achieve distinct cell and tissue responses. ER alpha generally functions as an activator of transcription while ER beta functions as a repressor.

ID gène: 2099

NCBI Accession: NP_000116

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly