PMPCB anticorps (AA 571-621)

N° du produit ABIN7450459

Détail du produit anti-PMPCB anticorps

Antigène: PMPCB (Peptidase (Mitochondrial Processing) beta (PMPCB))

Épitope: AA 571-621

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PMPCB est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-MPP11 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 571 and 621

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PMPCB

Antigène: PMPCB (Peptidase (Mitochondrial Processing) beta (PMPCB))

Autre désignation: MPP11 (PMPCB Produits)

Synonymes: anticorps Beta-MPP, anticorps MPP11, anticorps MPPB, anticorps MPPP52, anticorps P-52, anticorps Mppb, anticorps 3110004O18Rik, anticorps MGC78954, anticorps PMPCB, anticorps zgc:110738, anticorps Pmpcb, anticorps peptidase, mitochondrial processing beta subunit, anticorps peptidase (mitochondrial processing) beta, anticorps peptidase (mitochondrial processing) beta L homeolog, anticorps PMPCB, anticorps Pmpcb, anticorps pmpcb.L, anticorps pmpcb

Sujet: Background: M-phase phosphoprotein 11 is a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. MPP11 is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. MPP11 was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Additionally, chromosomal aberrations involving the DNAJC2 gene are associated with primary head and neck squamous cell tumors [taken from NCBI Entrez Gene (Gene ID: 27000)].

ID gène: 27000

NCBI Accession: NP_055192

UniProt: Q99543

Pathways: SARS-CoV-2 Protein Interactome