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UBQLN4 anticorps (AA 1-50)

UBQLN4 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7450868
  • Antigène Voir toutes UBQLN4 Anticorps
    UBQLN4 (Ubiquilin 4 (UBQLN4))
    Épitope
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50
    Reactivité
    • 21
    • 15
    • 13
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 21
    Lapin
    Clonalité
    • 19
    • 2
    Polyclonal
    Conjugué
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp UBQLN4 est non-conjugé
    Application
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Fonction
    Rabbit anti-UBQLN4/CIP75/Ubiquilin 4 Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogène
    Between AA 1 and 50
    Isotype
    IgG
    Top Product
    Discover our top product UBQLN4 Anticorps primaire
  • Indications d'application

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions
    For Research Use only
  • Concentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    UBQLN4 (Ubiquilin 4 (UBQLN4))
    Autre désignation
    UBQLN4/CIP75/Ubiquilin 4 (UBQLN4 Produits)
    Synonymes
    anticorps a1u, anticorps cip75, anticorps ubin, anticorps ubiquilin-4, anticorps A1U, anticorps A1Up, anticorps C1orf6, anticorps CIP75, anticorps UBIN, anticorps A1u, anticorps AI663987, anticorps RGD1308273, anticorps ubiquilin 4 L homeolog, anticorps ubiquilin 4, anticorps ubqln4.L, anticorps ubqln4, anticorps UBQLN4, anticorps Ubqln4
    Sujet
    Background: Ubiquilin-4 (UBQLN4) plays a role in the regulation of protein degradation via the ubiquitin-proteasome system (UPS). It mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. UBQLN4 Plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (By similarity). It acts as an adapter protein that recruits UBQLN1 to the autophagy machinery and mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:23459205) [taken from NCBI Entrez Gene (Gene ID: 56893)].
    ID gène
    56893
    UniProt
    Q9NRR5
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