MTMR6 anticorps (AA 571-621)

N° du produit ABIN7451181

Détail du produit anti-MTMR6 anticorps

Antigène: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Épitope: AA 571-621

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTMR6 est non-conjugé

Application: Immunoprecipitation (IP)

Fonction: Rabbit anti-MTMR6 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 571 and 621

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451181 has not performed satisfactorily when used for WB of MTMR6 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MTMR6.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MTMR6

Antigène: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Autre désignation: MTMR6 (MTMR6 Produits)

Synonymes: anticorps 4022440C11Rik, anticorps AI428804, anticorps AU041072, anticorps zgc:55289, anticorps wu:fi04a11, anticorps si:dkey-286f3.1, anticorps zgc:56405, anticorps myotubularin related protein 6, anticorps myotubularin related protein 8, anticorps MTMR6, anticorps Mtmr6, anticorps mtmr6, anticorps mtmr8

Sujet: Background: Myotubularin-related protein 6 (MTMR6) is a phosphatase that acts on lipids with a phosphoinositol headgroup. MTMR6 acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells [taken from the Universal Protein Resource (UniProt) Q9Y217].

ID gène: 9107

UniProt: Q9Y217

Pathways: Inositol Metabolic Process