SPG20 anticorps (AA 500-550)
Aperçu rapide pour SPG20 anticorps (AA 500-550) (ABIN7451351)
Antigène
Voir toutes SPG20 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 500-550
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Fonction
- Rabbit anti-SPG20 Antibody, Affinity Purified
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Homologie
- Mouse,Bovine
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Purification
- Affinity Purified
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Immunogène
- Between AA 500 and 550
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Isotype
- IgG
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Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-SPG20 antibody ABIN7450761.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
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Autre désignation
- SPG20
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Sujet
- Background: Spastic paraplegia 20 protein (SPG20) is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Mutations associated with the SPG20 gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome) [taken from NCBI Entrez Gene (Gene ID: 23111)].
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ID gène
- 23111
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UniProt
- Q8N0X7
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Pathways
- Regulation of Cell Size, SARS-CoV-2 Protein Interactome
Antigène
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