SPG20 anticorps (AA 500-550)

N° du produit ABIN7451351

L’anticorps anti-SPG20 Polyclonal produit chez le Lapin a été validé pour IP. Il convient pour la détection de SPG20 dans des échantillons provenant de Humain. }

Aperçu rapide pour SPG20 anticorps (AA 500-550) (ABIN7451351)

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPG20 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-SPG20 anticorps

Épitope: AA 500-550

Fonction: Rabbit anti-SPG20 Antibody, Affinity Purified

Homologie: Mouse,Bovine

Purification: Affinity Purified

Immunogène: Between AA 500 and 550

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-SPG20 antibody ABIN7450761.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SPG20

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Autre désignation: SPG20

Sujet: Background: Spastic paraplegia 20 protein (SPG20) is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Mutations associated with the SPG20 gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome) [taken from NCBI Entrez Gene (Gene ID: 23111)].

ID gène: 23111

UniProt: Q8N0X7

Pathways: Regulation of Cell Size, SARS-CoV-2 Protein Interactome