CDK5RAP3 anticorps (C-Term)

N° du produit ABIN7451694

Cet anticorps anti-CDK5RAP3 est un anticorps Lapin Polyclonal détectant CDK5RAP3 dans WB et IP. Adapté pour Humain.

Aperçu rapide pour CDK5RAP3 anticorps (C-Term) (ABIN7451694)

Antigène: CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK5RAP3 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-CDK5RAP3 anticorps

Épitope: C-Term

Fonction: Rabbit anti-CDK5RAP3 Antibody, Affinity Purified

Homologie: Mouse,Orangutan

Purification: Affinity Purified

Immunogène: between AA 450 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CDK5RAP3

Antigène: CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))

Autre désignation: CDK5RAP3

Sujet: Background: CDK5RAP3 (CDK5 regulatory subunit-associated protein 3) was identified as a protein that associates with the activating subunit of Cdk5, p25NCK5A. Cdk5 is a brain specific cyclin-dependent kinase important to mammalian brain development, however CDK5RAP3 appears to be widely expressed in human tissues. CDK5RAP3 appears to exhibit functions that extend beyond its association with Cdk5. CDK5RAP3 is involved in modulating the G2/M DNA damage checkpoint and can associate with and regulate the Cdk1-cyclin B1 complex. CDK5RAP3 has also been demonstrated to interact with and regulate the tumor suppressor ARF (alternative reading frame) to further play a role in cell cycle progression.

ID gène: 80279

NCBI Accession: NP_788276

UniProt: Q96JB5