DFFA anticorps (C-Term)

N° du produit ABIN7451735

L’anticorps anti-DFFA Polyclonal Lapin est utilisé pour la détection de DFFA dans des échantillons de Humain. Il a été validé pour WB et IP.

Aperçu rapide pour DFFA anticorps (C-Term) (ABIN7451735)

Antigène: DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DFFA est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-DFFA anticorps

Épitope: C-Term

Fonction: Rabbit anti-DFF35/DFFA Antibody, Affinity Purified

Homologie: Monkey

Purification: Affinity Purified

Immunogène: C-terminus

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur DFFA

Antigène: DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))

Autre désignation: DFF35/DFFA

Sujet: Background: DFF (DNA fragmentation factor) is the principle endonuclease responsible for DNA cleavage during apoptosis and exists as a heterodimer formed between the inhibitory subunit, DFF45, and the DNA nuclease, DFF40. DFF35/DFFA is a 35 kDa splice variant of the inhibitory subunit, DFF45. Similar to DFF45, DFF35 has been shown to heterodimerize with DFF40 and also negatively regulate its nuclease activity. In addition to regulating DFF40 activity, DFF35 has also been found to assist in the synthesis and folding of the DFF40 endonuclease.

ID gène: 1676

NCBI Accession: NP_998731

UniProt: O00273

Pathways: Apoptose, Caspase Cascade in Apoptosis