ORC1 anticorps (AA 811-861)

N° du produit ABIN7451914

Cet anticorps Lapin Polyclonal détecte spécifiquement ORC1 dans WB et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour ORC1 anticorps (AA 811-861) (ABIN7451914)

Antigène: ORC1 (ORC1L) (Origin Recognition Complex, Subunit 1 (ORC1L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORC1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-ORC1 anticorps

Épitope: AA 811-861

Fonction: Rabbit anti-ORC1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 811 and 861

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ORC1

Antigène: ORC1 (ORC1L) (Origin Recognition Complex, Subunit 1 (ORC1L))

Autre désignation: ORC1

Sujet: Background: ORC1 (origin recognition complex, subunit 1) is one of six subunits that make up the origin of recognition complex (ORC). The ORC serves as a scaffold for proteins involved in the initiation of DNA replication. Very recently, ORC1 has been found to perform a function independent of its role in DNA replication. In a screen using siRNAs for human ORC proteins to assess their roles in centrosome biology, it was found that ORC1 plays a key role in controlling centriole and centrosome copy number in human cells. ORC1 is also known as replication control protein 1, ORC1L, HSORC1, and PARC1.

ID gène: 4998

NCBI Accession: NP_004144

UniProt: Q13415

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA