USP20 anticorps (AA 863-913)

N° du produit ABIN7452141

Cet anticorps anti-USP20 est un anticorps Lapin Polyclonal détectant USP20 dans WB et IP. Adapté pour Humain et Souris.

Aperçu rapide pour USP20 anticorps (AA 863-913) (ABIN7452141)

Antigène: USP20 (Ubiquitin Specific Peptidase 20 (USP20))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP20 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-USP20 anticorps

Épitope: AA 863-913

Fonction: Rabbit anti-USP20/VDU2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 863 and 913

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur USP20

Antigène: USP20 (Ubiquitin Specific Peptidase 20 (USP20))

Autre désignation: USP20/VDU2

Sujet: Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific peptidase 20 (USP20) is a UBP and is also called von-Hippel-Lindau protein (pVHL) interacting deubiquitinating enzyme 2 (VDU2). pVHL is an E3 ubiquitin-ligase that ubiquitinates hypoxia-inducible factor (HIF)-1alpha. USP20/VDU2 functions to specifically deubiquitinate HIF-1alpha to increase expression of HIF-1alpha regulated genes.

ID gène: 10868

NCBI Accession: NP_006667

UniProt: Q9Y2K6

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling