RNF169 anticorps (AA 200-250)

N° du produit ABIN7452249

Cet anticorps anti-RNF169 est un anticorps Lapin Polyclonal détectant RNF169 dans IP. Adapté pour Humain.

Aperçu rapide pour RNF169 anticorps (AA 200-250) (ABIN7452249)

Antigène: RNF169 (Ring Finger Protein 169 (RNF169))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF169 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-RNF169 anticorps

Épitope: AA 200-250

Fonction: Rabbit anti-RNF169 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 200 and 250

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. ABIN7452249 has not performed satisfactorily when used for WB of RNF169 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of RNF169.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur RNF169

Antigène: RNF169 (Ring Finger Protein 169 (RNF169))

Autre désignation: RNF169

Sujet: Background: RING finger protein 169 (RNF169) is a probable E3 ubiquitin-protein ligase that acts as a negative regulator of the repair of double-strand breaks (DSBs) following DNA damage. RNF169 is recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSB repair [taken from the Universal Protein Resource (UniProt) Q8NCN4].

ID gène: 254225

NCBI Accession: NP_001092108

UniProt: Q8NCN4