FKBP5 anticorps (AA 225-275)

N° du produit ABIN7452330

Cet anticorps anti-FKBP5 est un anticorps Lapin Polyclonal détectant FKBP5 dans IP. Adapté pour Humain.

Aperçu rapide pour FKBP5 anticorps (AA 225-275) (ABIN7452330)

Antigène: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP5 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-FKBP5 anticorps

Épitope: AA 225-275

Fonction: Rabbit anti-FKBP5/FKBP51 Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: between AA 225 and 275

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-FKBP5/FKBP51 antibody A301-430A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur FKBP5

Antigène: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Autre désignation: FKBP5/FKBP51

Sujet: Background: FKBP5/FKBP51 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP5/FKBP51 exhibits peptidyl-prolyl cis-trans isomerase activity. The most studied role of FKBP5/FKBP51 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperones Hsp90 and Hsp70, FKBP5/FKBP51 is able to influence steroid-hormone binding affinity and transcriptional activity. Recently, FKBP5/FKBP51 has become of interest in the field of psychiatry due to its potential role in cortisol regulation and its relation to mood disorders.

ID gène: 2289

NCBI Accession: NP_004108

UniProt: Q13451