KIDINS220 anticorps (AA 1721-1771)
Aperçu rapide pour KIDINS220 anticorps (AA 1721-1771) (ABIN7452488)
Antigène
Voir toutes KIDINS220 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 1721-1771
-
Fonction
- Rabbit anti-ARMS Antibody, Affinity Purified
-
Homologie
- Rat
-
Purification
- Affinity Purified
-
Immunogène
- between AA 1721 and 1771
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
IP: 2 - 5 μg/mg lysate
WB: Not recommended
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C
-
Date de péremption
- 12 months
-
-
- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
-
Autre désignation
- ARMS
-
Sujet
- Background: Ankyrin repeat-rich membrane-spanning protein (ARMS) is also known as Kinase D-interacting substrate of 220 kDa (KIDINS220). ARMS Promotes prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Arms may play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. ARMS may play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration. ARMS has also been shown to modulate stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway [taken from the Universal Protein Resource (UniProt) Q9ULH0].
-
ID gène
- 57498
-
NCBI Accession
- NP_065789
-
UniProt
- Q9ULH0
Antigène
-