KIDINS220 anticorps (AA 1721-1771)

N° du produit ABIN7452488

Détail du produit anti-KIDINS220 anticorps

Antigène: KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

Épitope: AA 1721-1771

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIDINS220 est non-conjugé

Application: Immunoprecipitation (IP)

Fonction: Rabbit anti-ARMS Antibody, Affinity Purified

Homologie: Rat

Purification: Affinity Purified

Immunogène: between AA 1721 and 1771

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KIDINS220

Antigène: KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

Autre désignation: ARMS (KIDINS220 Produits)

Synonymes: anticorps ARMS, anticorps fj35h03, anticorps kidins220, anticorps zgc:63531, anticorps dZ119J18.2, anticorps wu:fj35h03, anticorps 3110039L19Rik, anticorps AI194387, anticorps AI316525, anticorps C330002I19Rik, anticorps mKIAA1250, anticorps kinase D interacting substrate 220, anticorps kinase D-interacting substrate 220, anticorps kinase D-interacting substrate 220b, anticorps kinase D-interacting substrate 220kDa, anticorps KIDINS220, anticorps Kidins220, anticorps kidins220b

Sujet: Background: Ankyrin repeat-rich membrane-spanning protein (ARMS) is also known as Kinase D-interacting substrate of 220 kDa (KIDINS220). ARMS Promotes prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Arms may play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. ARMS may play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration. ARMS has also been shown to modulate stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway [taken from the Universal Protein Resource (UniProt) Q9ULH0].

ID gène: 57498

NCBI Accession: NP_065789

UniProt: Q9ULH0