WWP1 anticorps (AA 300-350)

N° du produit ABIN7452554

Détail du produit anti-WWP1 anticorps

Antigène: WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

Épitope: AA 300-350

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWP1 est non-conjugé

Application: Immunoprecipitation (IP)

Fonction: Rabbit anti-WWP1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 300 and 350

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur WWP1

Antigène: WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

Autre désignation: WWP1 (WWP1 Produits)

Synonymes: anticorps AIP5, anticorps Tiul1, anticorps hSDRP1, anticorps 8030445B08Rik, anticorps SDRP1, anticorps WWP1, anticorps aip5, anticorps tiul1, anticorps hsdrp1, anticorps WW domain containing E3 ubiquitin protein ligase 1, anticorps WWP1, anticorps Wwp1, anticorps wwp1

Sujet: Background: WW domain-containing protein 1 (WWP1) functions as an E3 ubiquitin-protein ligase. WWP1 ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. WWP1 also ubiquitinates and promotes degradation of TGFBR1, TGFBR1 ubiquitination is enhanced by SMAD7, and WWP1 also ubiquitinates SMAD7 as well as SMAD6. [taken from the Universal Protein Resource (UniProt) Q9H0M0].

ID gène: 11059

NCBI Accession: NP_008944

UniProt: Q9H0M0