RAD17 anticorps (AA 564-614)

N° du produit ABIN7452689

L’anticorps Chèvre Polyclonal anti-RAD17 a été validé pour WB et IP. Il convient pour détecter RAD17 dans des échantillons de Humain.

Aperçu rapide pour RAD17 anticorps (AA 564-614) (ABIN7452689)

Antigène: RAD17

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD17 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-RAD17 anticorps

Épitope: AA 564-614

Fonction: Goat anti-Rad17 Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: between AA 564 and 614

Isotype: IgG

Information d'application

Indications d'application:

IP: 40 μL/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur RAD17

Antigène: RAD17

Autre désignation: Rad17

Sujet: Background: Rad17 is a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. [taken from the Universal Protein Resource (UniProt) O75943].

ID gène: 5884

NCBI Accession: NP_579917

UniProt: O75943