SMCP anticorps (AA 575-625)

N° du produit ABIN7452707

L’anticorps anti-SMCP Polyclonal Lapin est utilisé pour la détection de SMCP dans des échantillons de Humain. Il a été validé pour WB et IP.

Aperçu rapide pour SMCP anticorps (AA 575-625) (ABIN7452707)

Antigène: SMCP (Sperm Mitochondria Associated Cysteine Rich Protein (SMCP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMCP est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-SMCP anticorps

Épitope: AA 575-625

Fonction: Rabbit anti-MCSP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 575 and 625

Isotype: IgG

Information d'application

Indications d'application:

IP: 5 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SMCP

Antigène: SMCP (Sperm Mitochondria Associated Cysteine Rich Protein (SMCP))

Autre désignation: MCSP

Sujet: Background: Melanoma chondroitin sulfate proteoglycan (MCSP) is a cell-surface antigen expressed early in melanoma progression. It has been found to be involved in the spreading, invasion, and migration of human melanoma. MCSP influences melanoma behavior via the activation of the Cdc42 GTPase and phosphorylation of p130Cas. MCSP also activates signaling cascades involving FAK and ERK1/ERK2. In addition to its expression in melanoma cells, MCSP is also found in breast carcinomas, gliomas, neuroblastomas, and acute leukemias. MCSP is being considered as a target antigen for cancer immunotherapy.

ID gène: 1464

NCBI Accession: NP_001888

UniProt: Q6UVK1