DKC1 anticorps (AA 390-440)

N° du produit ABIN7452755

L’anticorps Lapin Polyclonal anti-DKC1 a été validé pour WB et IP. Il convient pour détecter DKC1 dans des échantillons de Humain.

Aperçu rapide pour DKC1 anticorps (AA 390-440) (ABIN7452755)

Antigène: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DKC1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-DKC1 anticorps

Épitope: AA 390-440

Fonction: Rabbit anti-DKC1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 390 and 440

Isotype: IgG

Information d'application

Indications d'application:

IP: 5 - 15 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur DKC1

Antigène: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Autre désignation: DKC1

Sujet: Background: Dyskeratosis congenita 1(DKC1) is also known as dyskerin. DKC1 is required for ribosome biogenesis and telomere maintenance. It is a probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. DKC1 is also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. Defects in DKC1 are a cause of dyskeratosis congenita X-linked recessive (XDKC), a rare progressive bone marrow failure syndrome [taken from the Universal Protein Resource (UniProt) O60832].

ID gène: 1736

NCBI Accession: NP_001354

UniProt: O60832

Pathways: Telomere Maintenance