Exportin 7 anticorps (AA 1-50)

N° du produit ABIN7452835

Cet anticorps Lapin Polyclonal détecte spécifiquement Exportin 7 dans WB et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Exportin 7 anticorps (AA 1-50) (ABIN7452835)

Antigène: Exportin 7 (XPO7)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Exportin 7 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Exportin 7 anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-RanBP16 Antibody, Affinity Purified

Homologie: Chicken,Orangutan

Purification: Affinity Purified

Immunogène: between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IP: 50-100 μL/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Exportin 7

Antigène: Exportin 7 (XPO7)

Autre désignation: RanBP16

Sujet: Background: RanBP16 mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. RanBP16 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. [taken from the Universal Protein Resource (UniProt) Q9UIA9].

ID gène: 23039

UniProt: Q9UIA9