RASAL1 anticorps (AA 754-804)

N° du produit ABIN7452836

L’anticorps Lapin Polyclonal anti-RASAL1 a été validé pour WB et IP. Il convient pour détecter RASAL1 dans des échantillons de Humain.

Aperçu rapide pour RASAL1 anticorps (AA 754-804) (ABIN7452836)

Antigène: RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASAL1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-RASAL1 anticorps

Épitope: AA 754-804

Fonction: Rabbit anti-RASAL1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 754 and 804

Isotype: IgG

Information d'application

Indications d'application:

IP: 50-100 μL/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur RASAL1

Antigène: RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

Autre désignation: RASAL1

Sujet: Background: RASAL1 is a member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, RASAL1 enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, RASAL1 is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010] [taken from NCBI Entrez Gene (Gene ID: 8437)].

ID gène: 8437

UniProt: O95294