ATXN7 anticorps (AA 842-892)

N° du produit ABIN7453039

Cet anticorps Lapin Polyclonal détecte spécifiquement ATXN7 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour ATXN7 anticorps (AA 842-892) (ABIN7453039)

Antigène: ATXN7 (Ataxin 7 (ATXN7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATXN7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ATXN7 anticorps

Épitope: AA 842-892

Fonction: Rabbit anti-Ataxin-7 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 842 and 892

Isotype: IgG

Information d'application

Indications d'application:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ATXN7

Antigène: ATXN7 (Ataxin 7 (ATXN7))

Autre désignation: Ataxin-7

Sujet: Background: Defects in ATXN7 are the cause of spinocerebellar ataxia type 7 (SCA7) also known as olivopontocerebellar atrophy III (OPCA III or OPCA3) or olivopontocerebellar atrophy with retinal degeneration. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. Ataxin 7 acts as a component of the STAGA transcription coactivator-HAT complex. It mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation [taken from the Universal Protein Resource (UniProt) O15265].

ID gène: 6314

NCBI Accession: NP_000324

UniProt: O15265