P4HB anticorps (AA 50-100)

N° du produit ABIN7453155

Cet anticorps anti-P4HB est un anticorps Lapin Polyclonal détectant P4HB dans WB. Adapté pour Humain et Souris.

Aperçu rapide pour P4HB anticorps (AA 50-100) (ABIN7453155)

Antigène: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P4HB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-P4HB anticorps

Épitope: AA 50-100

Fonction: Rabbit anti-P4HB/PDI Antibody, Affinity Purified

Homologie: Rat,Bovine,Orangutan

Purification: Affinity Purified

Immunogène: Between AA 50 and 100

Isotype: IgG

Information d'application

Indications d'application:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur P4HB

Antigène: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Autre désignation: P4HB/PDI

Sujet: Background: P4HB is a multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, P4HB seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. Inside the cell, it seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, P4HB functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, it facilitates aggregation (anti-chaperone activity) [taken from the Universal Protein Resource (UniProt) P07237].

ID gène: 5034

NCBI Accession: NP_000909

UniProt: P07237

Pathways: Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism