Transferrin Receptor anticorps (AA 125-175)

N° du produit ABIN7453217

L’anticorps Lapin Polyclonal anti-Transferrin Receptor a été validé pour WB. Il convient pour détecter Transferrin Receptor dans des échantillons de Humain.

Aperçu rapide pour Transferrin Receptor anticorps (AA 125-175) (ABIN7453217)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Transferrin Receptor anticorps

Épitope: AA 125-175

Fonction: Rabbit anti-TfR Antibody, Affinity Purified

Homologie: Dog,Horse,Orangutan

Purification: Affinity Purified

Immunogène: Between AA 125 and 175

Isotype: IgG

Information d'application

Indications d'application:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: TfR

Sujet: Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor (TR) into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site [taken from the Universal Protein Resource (UniProt) P02786].

ID gène: 7037

NCBI Accession: NP_003225

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis