PCNT anticorps (AA 175-225)

N° du produit ABIN7453380

Cet anticorps anti-PCNT est un anticorps Lapin Polyclonal détectant PCNT dans WB, IP et IF/ICC. Adapté pour Humain.

Aperçu rapide pour PCNT anticorps (AA 175-225) (ABIN7453380)

Antigène: PCNT (Pericentrin (PCNT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCNT est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC)

Détail du produit anti-PCNT anticorps

Épitope: AA 175-225

Fonction: Rabbit anti-Pericentrin/Kendrin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 175 and 225

Isotype: IgG

Information d'application

Indications d'application:

ICC-IF: 1:1,000 - 1:5,000. Formaldehyde or Acetone fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PCNT

Antigène: PCNT (Pericentrin (PCNT))

Autre désignation: Pericentrin/Kendrin

Sujet: Background: Pericentrin (PCNT) is a large centrosomal protein that binds calmodulin and mediates assembly of the mitotic spindle apparatus. Depletion of PCNT has been shown to cause apoptosis and activation of the G2/M checkpoint. Recently, mutations in the pericentrin gene have been identified as the cause of primordial dwarfism type II (MOPDII) and Seckel syndrome. Additionally, in cells of Seckel syndrome patients, PCNT has been found to be important to the DNA damage response and ATR-dependent checkpoint signaling.

ID gène: 5116

NCBI Accession: NP_006022

UniProt: O95613

Pathways: Sensory Perception of Sound, M Phase, SARS-CoV-2 Protein Interactome