ILK anticorps (AA 402-451)

N° du produit ABIN7453381

Cet anticorps Lapin Polyclonal détecte spécifiquement ILK dans WB, IP et IF/ICC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ILK anticorps (AA 402-451) (ABIN7453381)

Antigène: ILK (Integrin-Linked Kinase (ILK))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ILK est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC)

Détail du produit anti-ILK anticorps

Épitope: AA 402-451

Fonction: Rabbit anti-ILK Antibody, Affinity Purified

Homologie: Rat,Bovine,Guinea pig_10141,Orangutan

Purification: Affinity Purified

Immunogène: between AA 402 and 451

Isotype: IgG

Information d'application

Indications d'application:

ICC-IF: 1:100 - 1:500. Acetone fixation is recommended. Permeabilization is not recommended. Formaldehyde fixation is not recommended.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ILK

Antigène: ILK (Integrin-Linked Kinase (ILK))

Autre désignation: ILK

Sujet: Background: Integrin-linked kinase (ILK) is a serine/threonine kinase associated with the cytoplasmic domain of beta integrins and mediates integrin signaling from the extracellular matrix to the intracellular actin cytoskeleton. PKB/Akt and GSK-3beta are targets of ILK involved in integrin-mediated cell proliferation and cell survival. ILK has been shown to interact with Paxillin, PINCH-1, PINCH-2, and parvin to influence actin dynamics.

ID gène: 3611

NCBI Accession: NP_004508

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration