Prohibitin 2 anticorps (AA 1-50)

N° du produit ABIN7453408

Cet anticorps Lapin Polyclonal détecte spécifiquement Prohibitin 2 dans WB, IP et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour Prohibitin 2 anticorps (AA 1-50) (ABIN7453408)

Antigène: Prohibitin 2 (PHB2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prohibitin 2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-Prohibitin 2 anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-REA Antibody, Affinity Purified

Homologie: Mouse,Orangutan

Purification: Affinity Purified

Immunogène: between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 1 - 4 μg/mg lysate

WB: Not recommended. Use rabbit anti-REA Antibodies Cat. No. ABIN7450649 or Cat No. ABIN7449571.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Prohibitin 2

Antigène: Prohibitin 2 (PHB2)

Autre désignation: REA

Sujet: Background: REA (repressor of estrogen receptor activity), also known as prohibitin 2, has been shown to exhibit a variety of functions that includes mitochondrial chaperone activity, cell cycle regulation, and transcriptional regulation. REA localizes to the mitochondria and associates with mitochondrial complex I where it may play a role in mitochondrial metabolism. REA interacts with pRb to inhibit E2F-mediated transcription as well as the estrogen receptor to repress estrogen-dependent transcription via recruitment of histone deacetylases.

ID gène: 11331

NCBI Accession: NP_009204

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling