Geminin anticorps (C-Term)

N° du produit ABIN7453481

L’anticorps Lapin Polyclonal anti-Geminin a été validé pour WB, IP et IHC (fp). Il convient pour détecter Geminin dans des échantillons de Humain.

Aperçu rapide pour Geminin anticorps (C-Term) (ABIN7453481)

Antigène: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Geminin est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-Geminin anticorps

Épitope: C-Term

Fonction: Rabbit anti-Geminin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 160 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Geminin

Antigène: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Autre désignation: Geminin

Sujet: Background: Geminin has been identified as a protein that inhibits DNA replication during S, G2, and M phases in association with Cdt1 (chromatin licensing and DNA replication factor). Geminin prevents the binding of the MCM complex onto origins of replication, and its abundance is regulated by ubiquitin ligase activity of the APC/C (anaphase-promoting/cyclosome) complex.

ID gène: 51053

NCBI Accession: NP_056979

UniProt: O75496

Pathways: EGFR Signaling Pathway, DNA Replication