FBXW7 anticorps (AA 50-100)
Aperçu rapide pour FBXW7 anticorps (AA 50-100) (ABIN7453590)
Antigène
Voir toutes FBXW7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 50-100
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Fonction
- Rabbit anti-FBW7 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- between AA 50 and 100
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Isotype
- IgG
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anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibody
FBXW7 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 501-600) antibodyFBXW7 Reactivité: Humain, Souris, Rat WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Souris Monoclonal 3D1 unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-627) antibodyFBXW7 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 279-515) antibodyFBXW7 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-707) antibodyFBXW7 Reactivité: Humain IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-708) antibodyFBXW7 Reactivité: Humain WB, IHC, ELISA, IHC (p) Hôte: Souris Monoclonal 3D1 unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibodyFBXW7 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio), Drosophila melanogaster, Singe, Xenopus laevis, Hamster, Roussette (Chauve-souris), Poulet WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 251-300) antibodyFBXW7 Reactivité: Souris, Rat, Hamster WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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Autre désignation
- FBW7
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Sujet
- Background: FBW7 (F-box and WD repeat domain containing 7) is a member of the F-box family of proteins. The F-box is a protein-protein interaction motif first identified in cyclin F. F-box proteins associate with SCFs (Skp1-cullin-F-box protein ligase complexes) which are E3 ligases that ubiquitinate proteins and target them for proteasomal degradation. FBW7 has been found to bind and specifically target cyclin E and the Notch intracellular domain (NICD) for ubiquitination. Defects in FBW7 may contribute to tumorigenesis.
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ID gène
- 55294
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NCBI Accession
- NP_361014
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UniProt
- Q969H0
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Pathways
- Signalisation Notch, EGFR Signaling Pathway
Antigène
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