Cyclin T1 anticorps (AA 425-475)

N° du produit ABIN7453624

Cet anticorps Lapin Polyclonal détecte spécifiquement Cyclin T1 dans WB, IP et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour Cyclin T1 anticorps (AA 425-475) (ABIN7453624)

Antigène: Cyclin T1 (CCNT1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin T1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-Cyclin T1 anticorps

Épitope: AA 425-475

Fonction: Rabbit anti-Cyclin T1 Antibody, Affinity Purified

Homologie: Bovine,Horse,Chimpanzee

Purification: Affinity Purified

Immunogène: between AA 425 and 475

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Cyclin T1

Antigène: Cyclin T1 (CCNT1)

Autre désignation: Cyclin T1

Sujet: Background: Cyclin T1 is a regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of HIV or SIV infections, Cyclin T1 binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA) [taken from the Universal Protein Resource (UniProt) O60563].

ID gène: 904

NCBI Accession: NP_001231

UniProt: O60563