Fatty Acid Synthase anticorps (AA 1175-1225)

N° du produit ABIN7453706

L’anticorps Lapin Polyclonal anti-Fatty Acid Synthase a été validé pour WB, IP et IHC (fp). Il convient pour détecter Fatty Acid Synthase dans des échantillons de Humain.

Aperçu rapide pour Fatty Acid Synthase anticorps (AA 1175-1225) (ABIN7453706)

Antigène: Fatty Acid Synthase (FASN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fatty Acid Synthase est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-Fatty Acid Synthase anticorps

Épitope: AA 1175-1225

Fonction: Rabbit anti-FASN Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1175 and 1225

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Fatty Acid Synthase

Antigène: Fatty Acid Synthase (FASN)

Autre désignation: FASN

Sujet: Background: Fatty acid synthase (FASN) is a multifunctional protein that is mainly involved in catalyzing the synthesis of long-chain fatty acids. FASN has recently been viewed as an important protein involved in carcinogenesis as it has been found to be constitutively active in subsets of carcinomas and is associated with a poor prognosis. The inhibition of FASN activity in cancer cells promotes apoptosis and thus may play a role in maintaining cancer cell survival.

ID gène: 2194

NCBI Accession: NP_004095

UniProt: P49327

Pathways: AMPK Signaling