KDM3B anticorps (C-Term)

N° du produit ABIN7453716

Cet anticorps anti-KDM3B est un anticorps Lapin Polyclonal détectant KDM3B dans WB, IP et IHC (fp). Adapté pour Humain.

Aperçu rapide pour KDM3B anticorps (C-Term) (ABIN7453716)

Antigène: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM3B est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-KDM3B anticorps

Épitope: C-Term

Fonction: Rabbit anti-JMJD1B Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 1710 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KDM3B

Antigène: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Autre désignation: JMJD1B

Sujet: Background: JMJD1B is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD1B was identified as the 5qNCA gene that lies within a locus on chromosome 5 that is frequently deleted in myeloid leukemias and myelodysplasias. JMJD1B has been demonstrated to have growth suppressive activity and is implicated as a tumor suppressor gene.

ID gène: 51780

NCBI Accession: NP_057688

UniProt: Q7LBC6

Pathways: L'effet Warburg