ALIX anticorps (AA 818-868)

N° du produit ABIN7453859

L’anticorps anti-ALIX Polyclonal Lapin est utilisé pour la détection de ALIX dans des échantillons de Humain. Il a été validé pour WB, IP et IHC (fp).

Aperçu rapide pour ALIX anticorps (AA 818-868) (ABIN7453859)

Antigène: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALIX est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-ALIX anticorps

Épitope: AA 818-868

Fonction: Rabbit anti-ALIX Antibody, Affinity Purified

Homologie: Mouse,Rat

Purification: Affinity Purified

Immunogène: between AA 818 and 868

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ALIX

Antigène: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Autre désignation: ALIX

Sujet: Background: ALIX (ALG-2 interacting protein X) is thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of ALIX can block apoptosis. ALIX has been shown to bind to the PDCD6 (programmed cell death 6 interacting protein), a protein required for apoptosis, in a calcium-dependent manner. ALIX also binds to endophilins, proteins that regulate membrane shape during endocytosis [taken from NCBI Entrez Gene (Gene ID: 10015].

ID gène: 10015

NCBI Accession: NP_037506

UniProt: Q8WUM4

Pathways: Signalisation p53, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation