APOE anticorps (FITC)

N° du produit ABIN7454060

Cet anticorps anti-APOE est un anticorps Chèvre Polyclonal détectant APOE dans . Adapté pour Humain.

Aperçu rapide pour APOE anticorps (FITC) (ABIN7454060)

Antigène: APOE (Apolipoprotein E (APOE))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp APOE est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Clone: F10

Détail du produit anti-APOE anticorps (FITC)

Fonction: Goat anti-Human Apo E [F10] Antibody FITC Conjugated

Immunogène: Human Apolipoprotein E

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur APOE

Antigène: APOE (Apolipoprotein E (APOE))

Autre désignation: ApoE

Sujet: Background: Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels.

ID gène: 348

NCBI Accession: NP_000032

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism