NHEJ1 anticorps (AA 200-250)

N° du produit ABIN7454372

Détail du produit anti-NHEJ1 anticorps

Antigène: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Épitope: AA 200-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NHEJ1 est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-XLF Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 200 and 250

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-XLF antibody A300-730A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NHEJ1

Antigène: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Autre désignation: XLF (NHEJ1 Produits)

Synonymes: anticorps NHEJ1, anticorps zgc:85657, anticorps XLF, anticorps 1700029B21Rik, anticorps cernunnos, anticorps non-homologous end joining factor 1, anticorps non-homologous end joining factor 1 S homeolog, anticorps solute carrier family 23 member 3, anticorps nonhomologous end-joining factor 1, anticorps NHEJ1, anticorps nhej1.S, anticorps nhej1, anticorps SLC23A3, anticorps Nhej1

Sujet: Background: XRCC4-like factor (XLF) functions in DNA nonhomologous end joining (NHEJ) in double-strand break repair and immune system V(D)J recombination. Mutations of XLF in humans have been documented to result in immunodeficiency, growth retardation, and microcephaly. The yeast of homolog of XLF is Nej1. XLF has been shown to interact with the XRCC4 x DNA-ligase IV complex and is implicated in the DNA religation step of the NHEJ pathway.

ID gène: 79840

NCBI Accession: NP_079058

UniProt: Q9H9Q4

Pathways: Réparation de l'ADN