RAD23B anticorps (AA 125-175)

N° du produit ABIN7454444

Cet anticorps anti-RAD23B est un anticorps Lapin Polyclonal détectant RAD23B dans IP et IHC (fp). Adapté pour Humain.

Aperçu rapide pour RAD23B anticorps (AA 125-175) (ABIN7454444)

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD23B est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-RAD23B anticorps

Épitope: AA 125-175

Fonction: Rabbit anti-RAD23B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 125 and 175

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-RAD23B antibody A302-306A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur RAD23B

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Autre désignation: RAD23B

Sujet: Background: RAD23B is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. RAD23B was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

ID gène: 5887

NCBI Accession: NP_002865

UniProt: P54727

Pathways: Réparation de l'ADN