DCLRE1C anticorps (C-Term)

N° du produit ABIN7454515

L’anticorps Lapin Polyclonal anti-DCLRE1C a été validé pour WB et IHC (fp). Il convient pour détecter DCLRE1C dans des échantillons de Humain.

Aperçu rapide pour DCLRE1C anticorps (C-Term) (ABIN7454515)

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCLRE1C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-DCLRE1C anticorps

Épitope: C-Term

Fonction: Rabbit anti-Artemis Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: between AA 650 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur DCLRE1C

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Autre désignation: Artemis

Sujet: Background: Artemis is also known as DNA cross-link repair 1C protein (DCLRE1C) and functions as both an endo- and exo-nuclease involved in V(D)J recombination and double-strand break (DSB) repair. In addition to repair of double stranded breaks during V(D)J recombination, Artemis may also be required for repair of ionizing radiation induced DSBs. Mutations in Artemis have been found to be a cause of severe combined immunodeficiency (SCID).

ID gène: 64421

NCBI Accession: NP_001029027

UniProt: Q96SD1

Pathways: Réparation de l'ADN