INPPL1 anticorps (AA 100-150)

N° du produit ABIN7454647

L’anticorps Lapin Polyclonal anti-INPPL1 a été validé pour WB, IP et IHC (fp). Il convient pour détecter INPPL1 dans des échantillons de Humain et Souris.

Aperçu rapide pour INPPL1 anticorps (AA 100-150) (ABIN7454647)

Antigène: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INPPL1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-INPPL1 anticorps

Épitope: AA 100-150

Fonction: Rabbit anti-INPPL1/SHIP2 Antibody, Affinity Purified

Homologie: Rat

Purification: Affinity Purified

Immunogène: between AA 100 and 150

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 or Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur INPPL1

Antigène: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Autre désignation: INPPL1/SHIP2

Sujet: Background: INPPL1 (Inositol Polyphosphate Phosphatase-Like Protein 1) is a phosphatidylinositol phosphatase that negatively regulates phosphoinositide 3-kinase (PI3K) pathways related to numerous cell activities. INPPL1 plays a role in PI3K-dependent insulin, macrophage colony-stimulating factor, and EGF signaling. INPPL1 is also involved in actin cytoskeletal remodeling, actin dynamics, and neuritogenesis. INPPL1 interacts with SHC1 (src-homology domain) to mediate EGFR signaling.

ID gène: 3636

NCBI Accession: NP_001558

UniProt: O15357

Pathways: Platelet-derived growth Factor Receptor Signaling