BMI1 anticorps (AA 276-326)

N° du produit ABIN7454773

L’anticorps Lapin Polyclonal anti-BMI1 a été validé pour WB, IHC (fp) et IP. Il convient pour détecter BMI1 dans des échantillons de Humain et Souris.

Aperçu rapide pour BMI1 anticorps (AA 276-326) (ABIN7454773)

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMI1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Détail du produit anti-BMI1 anticorps

Épitope: AA 276-326

Fonction: Rabbit anti-BMI1 Antibody, Affinity Purified

Homologie: Chicken,Bovine,Cat,Orangutan

Purification: Affinity Purified

Immunogène: between AA 276 and 326

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur BMI1

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Autre désignation: BMI1

Sujet: Background: BMI1 (B lymphoma Mo-MLV insertion region 1 homolog) is a core component of the polycomb group (PcG) multiprotein PRC1 complex which plays an important role in transcriptional repression of gene expression during development. BMI1 association with RING protein 1B is important to the E3 ligase activity of RING1B in the PRC1 complex. BMI1 is an oncogene whose overexpression is associated with many types of human tumors and is a stem-cell marker and regulator of stem cell self-renewal.

ID gène: 648

NCBI Accession: NP_005171

UniProt: P35226

Pathways: Cycle Cellulaire, Autophagy