NOTCH2 anticorps (AA 2421-2471)

N° du produit ABIN7454805

Cet anticorps Lapin Polyclonal détecte spécifiquement NOTCH2 dans WB, IP et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour NOTCH2 anticorps (AA 2421-2471) (ABIN7454805)

Antigène: NOTCH2 (Notch 2 (NOTCH2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOTCH2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-NOTCH2 anticorps

Épitope: AA 2421-2471

Fonction: Rabbit anti-Notch2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 2421 and 2471

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NOTCH2

Antigène: NOTCH2 (Notch 2 (NOTCH2))

Autre désignation: Notch2

Sujet: Background: Notch2 is a member of the Notch family of transmembrane receptors. The Notch gene was first reported as a drosophila gene responsible for the presence of notches in the wingblades of a specific strain of flies. The Notch proteins mediate juxtacrine signals between adjacent cells and regulate cell fate determination during development. In mammals there are 4 Notch receptors (Notch 1-4). Like Notch1, Notch 2 is required for embryo viability. Although Notch1 and Notch 2 are functionally similar, they may not serve redundant functions in the cell.

ID gène: 4853

NCBI Accession: NP_077719

UniProt: Q04721

Pathways: Signalisation Notch, Stem Cell Maintenance