HEXIM1 anticorps (AA 309-359)

N° du produit ABIN7454896

L’anticorps Lapin Polyclonal anti-HEXIM1 a été validé pour WB, IP et IHC (fp). Il convient pour détecter HEXIM1 dans des échantillons de Humain et Souris.

Aperçu rapide pour HEXIM1 anticorps (AA 309-359) (ABIN7454896)

Antigène: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HEXIM1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-HEXIM1 anticorps

Épitope: AA 309-359

Fonction: Rabbit anti-HEXIM1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 309 and 359

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur HEXIM1

Antigène: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Autre désignation: HEXIM1

Sujet: Background: Hexamethylene bis-acetamide-inducible protein 1 (HEXIM1) is a transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA, HEXIM1sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. HEXIM1 may also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity [taken from the Universal Protein Resource (UniProt) O94992].

ID gène: 10614

NCBI Accession: NP_006451

UniProt: O94992