PARN anticorps (AA 589-639)

N° du produit ABIN7454930

Cet anticorps anti-PARN est un anticorps Lapin Polyclonal détectant PARN dans WB, IP et IHC (fp). Adapté pour Humain et Souris.

Aperçu rapide pour PARN anticorps (AA 589-639) (ABIN7454930)

Antigène: PARN (Poly A Specific Ribonuclease (PARN))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARN est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-PARN anticorps

Épitope: AA 589-639

Fonction: Rabbit anti-PARN Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: between AA 589 and 639

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PARN

Antigène: PARN (Poly A Specific Ribonuclease (PARN))

Autre désignation: PARN

Sujet: Background: Poly(A)-specific ribonuclease (PARN) is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. PARN prefers poly(A) as the substrate, hence, it efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. PARN is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons [taken from NCBI Entrez Gene (Gene ID: 5073)].

ID gène: 5073

NCBI Accession: NP_002573

UniProt: O95453