PHGDH anticorps (AA 1-50)

N° du produit ABIN7455052

L’anticorps Lapin Polyclonal anti-PHGDH a été validé pour WB, IP et IHC (fp). Il convient pour détecter PHGDH dans des échantillons de Humain et Souris.

Aperçu rapide pour PHGDH anticorps (AA 1-50) (ABIN7455052)

Antigène: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHGDH est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-PHGDH anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-PHGDH Antibody, Affinity Purified

Homologie: Bovine,Pig,Orangutan,Chimpanzee

Purification: Affinity Purified

Immunogène: Between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PHGDH

Antigène: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Autre désignation: PHGDH

Sujet: Background: D-3-phosphoglycerate dehydrogenase (PHGDH) is an enzyme involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptom [taken from NCBI Entrez Gene (Gene ID: 26227)].

ID gène: 26227

NCBI Accession: NP_006614

UniProt: O43175

Pathways: Metabolism of Steroid Hormones and Vitamin D, L'effet Warburg