AIMP1 anticorps (AA 262-312)

N° du produit ABIN7455058

L’anticorps Lapin Polyclonal anti-AIMP1 a été validé pour WB, IP et IHC (fp). Il convient pour détecter AIMP1 dans des échantillons de Humain et Souris.

Aperçu rapide pour AIMP1 anticorps (AA 262-312) (ABIN7455058)

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIMP1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-AIMP1 anticorps

Épitope: AA 262-312

Fonction: Rabbit anti-AIMP1/EMAPII/SCYE1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 262 and 312

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur AIMP1

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Autre désignation: AIMP1/EMAPII/SCYE1

Sujet: Background: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cell [taken from NCBI Entrez Gene (Gene ID: 9255)].

ID gène: 9255

NCBI Accession: NP_004748

UniProt: Q12904